A clinical trail to study the effect of inositols in achieving successful pregnancy among women with anovulation, if combined along with letrozole
- Conditions
- Health Condition 1: E282- Polycystic ovarian syndrome
- Registration Number
- CTRI/2023/03/050569
- Lead Sponsor
- Priyanka Yoga P
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1The age of the patient is between 20 yrs to 35 yrs
2Diagnosed as PCOS according to the Rotterdam criteria. (oligomenorrhoea hyperandrogenism (hirsutism, acne, or alopecia) or hyperandrogenemia (elevated levels of total or free T) and typical features of ovaries on ultrasound scan
3A normal hysterosalpingogram or laparoscopy has been documented
4Without any history of pelvic inflammatory disease or pelvic surgery
5Normal uterine cavity
6Male partners having semen analysis parameters within normal range, performed in preceding 6 months
7Without any treatment history of exogenous gonadotropin or metformin.
1Endocrine factors like hyperprolactinemia, premature ovarian failure, hypothalamic amenorrhea or uncorrected thyroid disease.
2Known cases of uncontrolled type 1 or 2 diabetes mellitus and/or hypertension.
3Allergic reactions or presence of other contraindications for the use of letrozole or CC.
4Other associated factors of infertility like a male factor, uterine factor or endometriosis.
5Myo-inositol use < 3 months prior to study enrolment
6Concomitant metformin use. Previous use is allowed with last use at least 6 weeks prior to randomization.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method