Investigation on the Effects of Acupuncture on Cognitive improvement in patients with Mild Cognitve Impairment using f-NIRS
- Conditions
- Mental and behavioral disorders
- Registration Number
- KCT0002451
- Lead Sponsor
- Dunsan Korean Medicine Hospital of Daejeon University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 24
<Common>
1. Aged from equal to or more than 45 to under 80 years old
2. Understand the purpose of the study and agree to participate
<Experimental group>
1. Patients who meet the Peterson diagnostic criteria of mild cognitive impairment (MCI) with memory problems at least for 3 months
2. At least 6 years of education
3. Hachinski ischemic score = 6
4. Korean Montreal Cognitive Assessment (MoCA-K) score = 22
5. Clinical dementia rating score 0.5 AND global deterioration scale score 2-3
<Normal control group>
1. Korean Montreal Cognitive Assessment (MoCA-K) score =23
1. Dementia by Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV)
2. History of neurological disorder that can cause cognitive decline (Parkinson's disease, stroke, cerebral hemorrhage, tumors, normal pressure hydrocephalus, etc.)
3. Received any treatment for MCI during the past 4 weeks
4. Patients who were involved in other clinical trials within 4 weeks
5. Those who have experienced hypersensitivity reactions after acupuncture treatment, or who are difficult to cooperate with acupuncture treatment
6. A patient who is likely to have a non-cooperative attitude in this clinical study or who is judged by the researcher to be unable to proceed with the study
7. Those who can not measure f-NIRS
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Korean Montreal Cognitive Assessment (MoCA-K)
- Secondary Outcome Measures
Name Time Method Changes of Oxy-Hb and deoxy-Hb in frontal lobe using f-NIRS;Alzheimer's disease assessment scale cognitive subscale (ADAS-cog);Accuracy, response rate and response time of working memory test