DOSE ranging in UPper limb rehabilitation post stroke (DOSE-UP)

Phase 1

Recruiting

• Conditions: Stroke; Physical Medicine / Rehabilitation - Occupational therapy; Physical Medicine / Rehabilitation - Physiotherapy; Stroke - Haemorrhagic; Stroke - Ischaemic

• Registration Number: ACTRN12620000215921
• Lead Sponsor: niversity of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-24
• Last Update Posted: 10 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

EARLY:
-Current inpatient at time of recruitment,
-Hospital diagnosis of stroke (ischemic or haemorrhagic) confirmed on clinical scanning (CT/MRI),
-Acute to early subacute phase of recovery, between 3 to 14 days post stroke onset,
-Aged 18 years or over,
-Upper limb impairment consistent with manual muscle testing of shoulder abduction and finger extension (SAFE) score of 2 to 7,
-Able to follow basic one stage commands in English,
-Able to provide written informed consent; note, family or authorised representative consent will be sought from individuals with insufficient comprehension to consent, defined by a score > 5 on Short Portable Mental State test, and
-Appropriate candidate for therapy in the home if required.

LATE:
-Discharged from the inpatient hospital setting,
-Diagnosis of stroke (ischemic or haemorrhagic),
-Late subacute phase of recovery, between 3 to 9 months post stroke,
-Aged 18 years or over,
-Upper limb impairment consistent with manual muscle testing of shoulder abduction and finger extension (SAFE) score of 2 – 7,
-Able to follow basic one stage commands in English,
-Able to provide written informed consent; note, family or authorised representative consent will be sought from individuals with insufficient comprehension to consent, defined by a score > 5 on Short Portable Mental State test, and
-Appropriate candidate for therapy in the home if required.

Exclusion Criteria

EARLY:
-Had a previous stroke(s) with residual deficits at current stroke onset,
-Diagnosis of other neurological conditions (e.g., dementia, Parkinson’s Disease, MS)
-Palliation of comorbid medical illness which in the opinion of the treating neurologist, it is deemed unlikely the patient will be able to actively participate in training,
-Concomitate condition that would interfere with participation (e.g., undergoing radiotherapy),
-Planned discharged to a location other than the community, Melbourne Health, Austin Health and Western Health, or
-Unable to commit to the upper limb training regimen.

LATE:
-Had a previous stroke(s) with residual motor deficits,
-Diagnosis of other neurological conditions (e.g., dementia, Parkinson’s Disease, MS)
-Concomitate condition that would interfere with participation (e.g., undergoing a treatment radiotherapy), or
-Unable to travel and commit to the upper limb training regimen.

Study & Design

• Study Type: Interventional
• Study Design: Not specified