To compare the effects of standard Vs guided PEEP intraoperatively on lung complications after surgery in patients undergoing upper abdominal surgery
- Registration Number
- CTRI/2023/03/050467
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
1.Patients of ASA Physical Status I – III scheduled for elective upper abdominal surgery with expected duration of surgery more than 1 hour under general anaesthesia.
2.BMI between 18 and 35 kg/m2.
3.Age more than 18 years.
1.Patient refusal
2.Emergency surgeries
3.Previous history of any thoracic surgeries
4.Pregnancy
5.Any nasopharyngeal or oropharyngeal pathologies
6.Contraindications to nasogastric tube placement.
7.Any laparoscopic surgeries being converted to open surgeries.
8.Chronic Obstructive Pulmonary Disease, Bronchial Asthma or other chronic lung diseases
9.Deformity of chest wall or thoracic spine
10.preoperative diagnosis of pneumonia
11.BMI <18 kg/m2 or > 35 kg/m2
12.Significant cardiac, renal or hepatic diseases
13.Intraoperative massive blood loss (blood loss >40ml/kg) or massive transfusion ( >8 PRBC transfusion during surgery)
14.Patients on high dose vasopressor (noradrenaline > 10mcg/min or equivalent)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post operative pulmonary complications till day 5 as per Melbourne group score greater than or equal to 2Timepoint: Till day 5
- Secondary Outcome Measures
Name Time Method 2.Intra operative and post operative oxygenation status measured by PaO2/FiO2 ratio after peep titration. <br/ ><br> <br/ ><br>3.Post operative atelectasis measured by Lung Ultrasound Score. <br/ ><br> <br/ ><br>4.Any treatment related adverse effects. <br/ ><br> <br/ ><br>Timepoint: Anaesthesia care time during surgery