NCT02638844已完成不适用
ARDStrain : Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome
Central Hospital, Nancy, France1 个研究点 分布在 1 个国家目标入组 49 人开始时间: 2015年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 49
- 试验地点
- 1
- 主要终点
- Measure of longitudinal peak systolic strain
研究概览
简要总结
Assessment of right ventricular (RV) function in patients with acute respiratory syndrome (ARDS) is warranted because RV failure is frequent and associated with worse outcome. Transthoracic echocardiography is the cornerstone of RV assessment but it remains challenging. Quantification of RV deformation by speckle-tracking imaging echocardiography (STE) is a widely available and reproducible technique that readily provides an integrated analysis of all segments of the RV. This study aims to investigate the accuracy of STE-derived strain parameters in assessing RV function during ARDS.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with moderate or severe ARDS (Berlin definition)
- •receiving mechanical ventilation (>48h estimated length)
- •Transthoracic echocardiography performed during the first 36h after ICU admission
排除标准
- •pregnancy
- •protected or deprived of Liberty major
- •chronic respiratory disease
- •history of clinical right heart failure
- •chronic heart failure with LVEF < 35%
- •severe valvular heart disease
- •under 18 or protected-adults
结局指标
主要结局
Measure of longitudinal peak systolic strain
时间窗: up to 36 hours after Intensive Care Unit admission
次要结局
- Ventilator-free days(28 days)
- Mortality(28 days)
- Measure of PaO2/FiO2 ratio(up to 36 hours after Intensive Care Unit admission)
研究者
研究点 (1)
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