Acute cardiometabole risico’s tijdens de behandeling met haloperidol bij ouderen.
Suspended
- Conditions
- ouderen, delier, antipsychoticaelderly, delirium, antipsychotics
- Registration Number
- NL-OMON21267
- Lead Sponsor
- Tergooiziekenhuizen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 128
Inclusion Criteria
1. Age 70 years and older admitted for hip fracture or other fall-related fractures;
2. Inclusion within 72 hours after admission;
Exclusion Criteria
1. Use of an antipsychotic agent within 90 days before admission;
2. Start or dose change in of any anticoagulants, Qtc prolongation drugs, antidiabetic drugs, antihypertensive drugs or cholesterol lowering drugs;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. QTc- prolongation measured with holter ECG;<br /><br>2. Serum NT-proBNP, glucose, triglycerides;<br /><br>3. Closure time.
- Secondary Outcome Measures
Name Time Method 1. QTc- prolongation measured with ECG;<br /><br>2. Serum concentration haloperidol;<br /><br>3. DDD;<br /><br>4. Total antipsychotic expose;<br /><br>5. DNA profile.