Improving resilience with whole grain wheat - graandioos

Wageningen Universiteit0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•In order to be eligible to participate in this study, a subject must meet the following inclusion criteria:
•Males or postmenopausal females (target 50: 50 for both genders)
•For females: menstrual cycle absent for more than 1 year
•Age 45-70yrs
•BMI between 25 and 35 kg/m2
•Signed informed consent
•Normal food habit of bread and cereal consumption

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•Not having a general practitioner
•Having a history of medical or surgical events that may affect the study outcome
•Use of cholesterol lowering medication
•Mental status that is not compatible with proper conduct of the study
•Aversion, intolerance to gluten, whole wheat or other items in the intervention products
•Alcohol consumption of > 21 glasses a week
•Abuse of drugs
•Recent use of antibiotics (<1 month prior to day 01 of the study)
•Reported unexplained weight loss or weight gain of > 5 kg in the month prior to pre-study screening
•Reported slimming or medically prescribed diet
•Reported vegan or macrobiotic life-style
•Not willing to give up blood donation during the study
•Personnel of Wageningen University, department of Human Nutrition, their partner and their first and second degree relatives
•Current participation in other research
•Contraindication for MRI
•Having blood vessels that make it difficult for inserting a cannula

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