A randomized double blinded study comparing block characteristics of mixture of lignocaine and ropivacaine versus sequential lignocaine followed by ropivacaine in patients undergoing upper limb surgery under supra-clavicular brachial plexus nerve block.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Percentage of patients with complete sensory block in all 4- nerve areas (musculo-cutaneous, median, radial, ulnar) at 10 minutes post injection.
研究概览
简要总结
Studies have beenconducted on use of ropivacaine, bupivacaine and lignocaine in variouscombinations in various nerve blocks and neuraxial blocks. There is no clearconsensus on appropriate use of mixtures of these agents specially in brachialplexus nerve blocks. Ropivacaine is an established safer, equally efficaciousalternative to bupivacaine. We intend to compare use of a short acting druglignocaine and long acting drug Ropivacaine as a mixture versus undilutedsequential injections on block characteristics of ultrasound guided nerve blockfor upper limb surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Weighing more than 60 kg, planned for unilateral upper limb surgery.
排除标准
- •Patient refusal, coagulation or bleeding disorders, local site infection, any nerve injury/ neuropraxia/ paralysis, history of allergy or anaphylaxis to ropivacaine or lignocaine, pregnant females and block failure due to technical reasons.
结局指标
主要结局
Percentage of patients with complete sensory block in all 4- nerve areas (musculo-cutaneous, median, radial, ulnar) at 10 minutes post injection.
时间窗: Percentage of patients with complete sensory block in all 4- nerve areas (musculo-cutaneous, median, radial, ulnar) at 10 minutes post injection.
次要结局
- Time to onset of first sensory block, time to onset of complete sensory block, time to complete motor block, duration of analgesia, procedure time, block failures, duration of sensory block, duration of motor block, and complication rates ( last three reading will be observed in post-anaesthesia care unit every one hour and in ward every 2 hours by in-charge nurse or resident.(Time to onset of first sensory block, time to onset of complete sensory block, time to complete motor block, duration of analgesia, procedure time, block failures, duration of sensory block, duration of motor block, and complication rates ( last three reading will be observed in post-anaesthesia care unit every one hour and in ward every 2 hours by in-charge nurse or resident.)