A study comparing mixture of local anaesthetic agents lignocaine and ropivacaine versus sequential lignocaine followed by ropivacaine in patients undergoing surgery on hands and arms under regional anaesthesia.
- Conditions
- Acquired deformity of musculoskeletal system, unspecified,
- Registration Number
- CTRI/2020/03/024013
- Lead Sponsor
- Mridul Dhar
- Brief Summary
Studies have beenconducted on use of ropivacaine, bupivacaine and lignocaine in variouscombinations in various nerve blocks and neuraxial blocks. There is no clearconsensus on appropriate use of mixtures of these agents specially in brachialplexus nerve blocks. Ropivacaine is an established safer, equally efficaciousalternative to bupivacaine. We intend to compare use of a short acting druglignocaine and long acting drug Ropivacaine as a mixture versus undilutedsequential injections on block characteristics of ultrasound guided nerve blockfor upper limb surgeries.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 66
Weighing more than 60 kg, planned for unilateral upper limb surgery.
Patient refusal, coagulation or bleeding disorders, local site infection, any nerve injury/ neuropraxia/ paralysis, history of allergy or anaphylaxis to ropivacaine or lignocaine, pregnant females and block failure due to technical reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of patients with complete sensory block in all 4- nerve areas (musculo-cutaneous, median, radial, ulnar) at 10 minutes post injection. Percentage of patients with complete sensory block in all 4- nerve areas (musculo-cutaneous, median, radial, ulnar) at 10 minutes post injection.
- Secondary Outcome Measures
Name Time Method Time to onset of first sensory block, time to onset of complete sensory block, time to complete motor block, duration of analgesia, procedure time, block failures, duration of sensory block, duration of motor block, and complication rates ( last three reading will be observed in post-anaesthesia care unit every one hour and in ward every 2 hours by in-charge nurse or resident. Time to onset of first sensory block, time to onset of complete sensory block, time to complete motor block, duration of analgesia, procedure time, block failures, duration of sensory block, duration of motor block, and complication rates ( last three reading will be observed in post-anaesthesia care unit every one hour and in ward every 2 hours by in-charge nurse or resident.
Trial Locations
- Locations (1)
AIIMS Rishikesh, Department of Anaesthesiology
🇮🇳Dehradun, UTTARANCHAL, India
AIIMS Rishikesh, Department of Anaesthesiology🇮🇳Dehradun, UTTARANCHAL, IndiaDr Mridul DharPrincipal investigator9717778374mriduldhar@hotmail.com