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临床试验/NCT03544346
NCT03544346Unknown不适用

An Investigation Into the Long-term Brain Health of Retired Professional Rugby Players, With a History of Concussion/Head Impact Exposure

University of Dublin, Trinity College0 个研究点目标入组 200 人开始时间: 2018年6月18日最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
主要终点
Brain Health Assessment

研究概览

简要总结

There has been significant recent interest on the issue of brain health in athletes. Participation in sports is generally viewed as extremely positive. Consistent evidence supports associations among exercise, cognitive vitality, neural functioning and decreased risk of cognitive decline. However, In the last decade, a dramatic shift in both public and scientific perception around the long-term consequences of concussion is evident. Rugby is a popular full-contact sport played throughout the world at varying levels of competition, including professional level. The game exposes players to inherent risk of injury including repetitive head impacts, due to the high number of collisions and tackles involved. Perhaps not surprisingly, given the physical nature of the sport, rugby has one of the highest rates of concussion of all full-contact sports. Evidence from a recent meta-anaysis found the incidence of concussion to be 4.73 per 1000 player match hours. Given the high incidence of concussion that has been reported in the literature to date, the issue of concussion and repeated head impact exposure is of particular concern in rugby.

Comprehensive investigation of cognition in living retired sports persons with previous exposure to repetitive head impact is noticeably lacking in the literature to date. Findings are inconsistent and investigations are shrouded by consistent methodological biases and flaws, reducing the overall quality of the studies. Relatively little research has been conducted on the long-term effects of repetitive mild TBI or sports concussion on the retired athlete's brain health with ageing. The potential long-term consequences are poorly understood and warrant more research. This study aims to investigate the brain health of retired rugby players in comparison to retired rowers who have achieved the same levels of exercise, without exposure to SRCs

详细描述

The primary aim of this study is to investigate brain health and wellness of retired professional Irish rugby players in comparison to retired professional Irish rowers.

Objectives:

The objectives will be to:

Obtain detailed demographic and overall health information from the retired rugby players and retired rowers.

Use a battery of cognitive function tests to assess the cognitive health of the retired rugby players and retired rowers.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

性别
Male
接受健康志愿者

入选标准

  • Male A retired professional rugby player (no age limit), who has played at least one season of professional rugby. A retired international rower (no age limit), who completed and trained full time for at least one season.
  • Athletes who have given informed consent and are willing to participate in the study.

排除标准

  • You have a history of a non-sports related moderate to severe concussion or brain injury (eg a motor vehicle accident) You have had a concussion in the last year. You have had treatment of chemotherapy or radiotherapy in last 12 months. You have a bleeding disorder (will exclude you from blood sampling only).

结局指标

主要结局

Brain Health Assessment

时间窗: 1 hour

Investigating cognitive functioning

次要结局

  • Concussion History Assessment(20 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Joice Cunningham

Ms Joice Cunningham (Phd Candidate)

University of Dublin, Trinity College

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