The Interactive Physical and Cognitive Exercise System (iPACES™): A Neuro-exergame for Preventing Alzheimer's and Ameliorating Cognitive Impairment

Union College, New York1 site in 1 country31 target enrollmentMarch 4, 2017

ConditionsAlzheimer Disease, Early Onset MCI Aging Mild Cognitive Impairment Neurocognitive Disorder Cognitive Impairment Cognitive Change

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Alzheimer Disease, Early Onset
Sponsor: Union College, New York
Enrollment: 31
Locations: 1
Primary Endpoint: executive function composite score
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise. In particular, this study will investigate the possible benefits of physical exercise (such as pedaling an under-table stationary elliptical) or mental exercise (such as playing a videogame on a portable tablet), or combining these activities together (as in the iPACES™ exergame).

Registry

clinicaltrials.gov

Start Date

March 4, 2017

End Date

June 30, 2022

Last Updated

6 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Union College, New York

Responsible Party

Principal Investigator

Cay Anderson-Hanley, PhD

Associate Professor

Union College, New York

Eligibility Criteria

Inclusion Criteria

•co-residing older adults (e.g., spouses, partners, roommates, relatives)
•both at least 50 years of age
•normative/typical cognitive function or those with Mild Cognitive Impairment (MCI) or mild Neurocognitive Disorder (mNCD) or early Alzheimer's disease
•adequate vision and dexterity for on-screen assessments
•able to pedal an under-table elliptical
•permission of primary care provider and cardiologist (if applicable)

Exclusion Criteria

•history of seizure
•Parkinson's disease
•significant dementia/memory loss

Outcomes

Primary Outcomes

executive function composite score

Time Frame: change over time from baseline to 3 months

comprised of scores from Stroop, Trails, and Flanker

Secondary Outcomes

Sit-Stand Test(change over time in score from baseline to 3 months)
brain-derived neurotrophic factor (BDNF)(change over time from baseline to 3 months)