NCT01038726已完成不适用
Neural Effects of Exercise, Cognitive, or Combined Training in AD At-Risk Elders
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 2
- 主要终点
- Brain activation patterns measured by functional MRI
研究概览
简要总结
The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •First or Second-degree relative of someone with Alzheimer's Disease
- •Not currently engaging in regular exercise
- •Able to undergo an MRI
- •Fluent in English
排除标准
- •Neurological illnesses/conditions
- •Medical illness/conditions that may affect brain function
- •Any unstable or severe cardiovascular disease or asthmatic condition
- •Severe depressive symptoms
- •Inability to walk unassisted
结局指标
主要结局
Brain activation patterns measured by functional MRI
时间窗: baseline and 12 weeks
次要结局
- Neuropsychological Testing(baseline and 12 weeks)
- Exercise assessment(baseline and 12 weeks)
研究者
研究点 (2)
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