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Clinical Trials/NCT01038726
NCT01038726
Completed
N/A

Neural Effects of Exercise, Cognitive, or Combined Training in AD At-Risk Elders

The Cleveland Clinic1 site in 1 country108 target enrollmentDecember 2009
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ConditionsAgingAlzheimer's Disease

Overview

Phase
N/A
Intervention
Not specified
Conditions
Aging
Sponsor
The Cleveland Clinic
Enrollment
108
Locations
1
Primary Endpoint
Brain activation patterns measured by functional MRI
Status
Completed
Last Updated
12 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.

Registry
clinicaltrials.gov
Start Date
December 2009
End Date
September 2012
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •First or Second-degree relative of someone with Alzheimer's Disease
  • •Not currently engaging in regular exercise
  • •Able to undergo an MRI
  • •Fluent in English

Exclusion Criteria

  • •Neurological illnesses/conditions
  • •Medical illness/conditions that may affect brain function
  • •Any unstable or severe cardiovascular disease or asthmatic condition
  • •Severe depressive symptoms
  • •Inability to walk unassisted

Outcomes

Primary Outcomes

Brain activation patterns measured by functional MRI

Time Frame: baseline and 12 weeks

Secondary Outcomes

  • Neuropsychological Testing(baseline and 12 weeks)
  • Exercise assessment(baseline and 12 weeks)

Study Sites (1)

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