Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery

Not yet recruiting

• Conditions: Minimal Flow Anesthesia; Low Flow Anesthesia; Robotic Assisted Laparoscopic Abdominal Surgery
• Interventions: Other: blood gas analysis

• Registration Number: NCT06520943
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery. The comparison will be based on hemodynamic and respiratory parameters. The secondary aim of our study is to compare the two different fresh gas flow methods in terms of inhalation agent consumption and soda lime consumption.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-09
• Study Start: 2024-07-15
• Study First Submitted QC: 2024-07-23
• Last Update Submitted: 2024-07-23
• Study First Posted: 2024-07-25
• Last Update Posted: 2024-07-25
• Primary Completion: 2024-09-01
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Patients undergoing robotic-assisted abdominal surgery

Exclusion Criteria

• serious cardiac, respiratory, hepatic, renal, or mental disorders;
• hearing problems;
• anxiety, depression, or other psychiatric conditions;
• patient's request to leave the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 2	blood gas analysis	After intubation, a fresh gas flow of 3 L/min will be applied for the first 20 minutes and then reduced to 1 L/min.
Group 1	blood gas analysis	After intubation, a fresh gas flow of 3 L/min will be applied for the first 20 minutes and then reduced to 0.5 L/min.

Primary Outcome Measures

Name	Time	Method
partial oxygen pressure	from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)	PO2 from blood gas analysis
inspiratory O2 concentration	from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)	inspiratory O2 concentration is measured from anesthesia machine monitor

Secondary Outcome Measures

Name	Time	Method
changes in liver and kidney function tests from the preoperative values to 48 hours postoperative	postoperative 1st day	to determine the changes in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine from the preoperative values to 48 hours postoperative
desflurane consumption	3th hour	desflurane consumption

Trial Locations

Locations (1)

Ankara City Hospital; 🇹🇷 Ankara, Turkey