Low Flow Anesthesia Without Initial High Flow Phase

Not Applicable

Completed

• Conditions: Low Flow Anesthesia; Volatile Anesthetic Consumption
• Interventions: Procedure: Conventional Low flow Anesthesia; Procedure: Low Flow Anesthesia with fixed fresh gas flow rate

• Registration Number: NCT03955406
• Lead Sponsor: Kahramanmaras Sutcu Imam University

Brief Summary

The aim of the study is to compare the effectiveness of conventional low flow anesthesia (LFA) with initial high fresh gas flow ( 4L/min) for 10 minutes and LFA with fixed fresh gas flow rate (1L/min).

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-05-16
• Study First Submitted QC: 2019-05-16
• Study First Posted: 2019-05-20
• Study Start: 2019-05-22
• Status Verified: 2019-07
• Primary Completion: 2019-07-02
• Study Completion: 2019-07-02
• Last Update Submitted: 2019-07-09
• Last Update Posted: 2019-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• ASA 1-3
• scheduled for surgery under general anesthesia with endotracheal intubation

Exclusion Criteria

• hemodynamic instability
• emergency cases
• expected anesthesia duration < 60 min
• patient refusal

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional group	Conventional Low flow Anesthesia	After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 6% with fresh gas flow rate 4 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 1% higher value than the EtAA concentration required to achieve 0.7 MAC. And after 10 minutes fresh gas flow rate will be reduced to 1L/min.
Fixed Fresh Gas Flow Rate group	Low Flow Anesthesia with fixed fresh gas flow rate	After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 18% with fresh gas flow rate 1 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 2% higher value than the EtAA concentration required to achieve 0.7 MAC.

Primary Outcome Measures

Name	Time	Method
The time required to reach 0.7 MAC	perioperative
number of adjustments made to the vaporizer settings	perioperative	MAC will be held between 0.6-0.8 with adjustments at the vaporizer

Secondary Outcome Measures

Name	Time	Method
anesthetic agent consumption	perioperative	desfluane consumption at the first hour and at the end of the surgery wil be recorded

Trial Locations

Locations (1)

Kahramanmaras Sutcu Imam University; 🇹🇷 Kahramanmaras, In The USA Or Canada, Please Select..., Turkey