跳至主要内容
临床试验/CTRI/2024/07/071286
CTRI/2024/07/071286招募中不适用

Evaluating The Efficacy of Multimodal Physiotherapy In Patients With Idiopathic Facial Palsy Based On Their Electroneurographic Quotient

Bihar Neuro1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年7月30日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
100
试验地点
1
主要终点
Facial Nerve Conduction test (ENoG), Blink Reflex analysis and functional outcomes evaluation with House–Brackmann (H-B) grading system and Sunny Brook Scale and 3T MRI brain along with constructive interference

研究概览

简要总结

Bell’s palsy is the most common form of acute spontaneous peripheral facial paralysis and can present as unilateral weakness or paralysis of the face. Its spontaneous recovery rate is high, and proper management results in a good prognosis without sequelae . The initial degree of facial paralysis has been regarded as one of the most important prognostic factors for recovery . In clinical practice, the degree of initial facial paralysis is determined by the House-Brackmann (H-B) grade or Sunny brook scale of Facial grading. Facial nerve electrodiagnostics is a well-established and important tool for decision making as it can assist in diagnosis, assess the lesion severity, and aid in decision making. Even though there are evidence regarding efficacy of various physiotherapeutic modalities in management of IFP, still electrical stimulation is the primary treatment physiotherapeutic choice in management of Bell’s Palsy, anecdotal evidence suggests potential negative effects of electrical stimulation in increasing aberrant reinnervation and synkinesis. The objective of the present study is to categorise the extent of nerve damage based on electrophysiological studies and thereafter provide physiotherapeutic treatment based on the degree of damage.

研究设计

研究类型
Interventional
分配方式
Other
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
10.00 Year(s) 至 59.00 Year(s)(—)
性别
All

入选标准

  • Patients with acute onset due to idiopathic causes.

排除标准

  • Patient having undergone physiotherapeutic treatment for facial palsy somewhere else.
  • Upper motor neuron pathology-induced facial palsy.
  • History of recurrent IFP.
  • History of recent head or neck injury.
  • No history of ongoing otitis media or ear discharge.
  • Non co-operative patient.

结局指标

主要结局

Facial Nerve Conduction test (ENoG), Blink Reflex analysis and functional outcomes evaluation with House–Brackmann (H-B) grading system and Sunny Brook Scale and 3T MRI brain along with constructive interference

时间窗: Day 0 ; day of admission | Day 10-14 post Bells palsy | Consecutive Day 21 from date of onset till full recovery

in steady state (CISS) protocol for facial nerve.

时间窗: Day 0 ; day of admission | Day 10-14 post Bells palsy | Consecutive Day 21 from date of onset till full recovery

次要结局

  • Degeneration index/ Electroneurographic quotient(at the time of)

研究者

发起方
Bihar Neuro
申办方类型
Private hospital/clinic
责任方
Principal Investigator
主要研究者

Dr Gunjan Kumar

Bihar Neuro

研究点 (1)

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