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The Right Care, for the Right Patient, at the Right Time, by the Right Provider: A Value-based Comparison of the Management of Ambulatory Patients With Acute Health Concerns in walk-in Clinics, Primary Care Physician Practices and Emergency Departments

Recruiting
Conditions
Emergency Services, Hospital
Quality of Care
Costs
Ambulatory Care
Interventions
Other: On-site recruitment (information and consent) following a random sampling recruitment schedule
Other: First phone call 1-3 days after the initial visit
Other: Second phone call 8-14 days after the initial visit
Registration Number
NCT05892666
Lead Sponsor
Simon Berthelot
Brief Summary

INTRODUCTION Whereas low-acuity ambulatory patients have been cited as a source of emergency department (ED) overuse or misuse, it is argued that patient evaluation in the ED may end up being more cost-effective. The COVID-19 pandemic has complicated the debate by shifting primary care practices (PCP) and walk-in clinics (WIC) towards telemedicine, a consultation modality presumed to be more efficient under the circumstances.

OBJECTIVES To compare, from patient and healthcare system perspectives, the value of the care received in person or by telemedicine in EDs, WICs and PCPs by ambulatory patients presenting with one the following complaints: 1) Acute diarrheas; 2) Sore throat; 3) Nasal congestion; 4) Increased or purulent nasal discharge; 5) Earache or ear discharge; 6) Shortness of breath; 7) Cough; 8) Increased or purulent sputum; 9) Muscle aches; 10) Anosmia; 11) Dysgeusia; 12) Burning urine; 13) Urinary frequency and urgency; 14) Dysuria; 15) Limb traumatic injury; 16) Cervical, thoracic or lumbar back pain; and 17) Fever

METHODS The investigators shall perform a multicenter prospective cohort study in Québec and Ontario. In phase 1, a time-driven activity-based costing method will be applied at each of 14 study sites. This method uses time as a cost driver to allocate direct costs (e.g. medication), consumable expenditures (e.g. needles, office supplies), overhead (e.g. building maintenance) and physician charges to patient care. The cost of a care episode thus will be proportional to the time spent receiving the care. At the end of this phase, a list of care process costs (e.g. triage, virtual medical assessment) will be generated and used to calculate the cost of each consultation during phase 2, in which a prospective cohort of patients will be monitored in order to compare the care received in EDs, WICs and PCPs. Research assistants will recruit eligible participants during the initial in-person or virtual visit. They will complete the collection using local medical records and provincial databases. Participants will be contacted by phone for follow-up questionnaires 1-3 and 8-14 days after their visit. Patients shall be aged 18 years and over, ambulatory throughout the care episode and have one of the targeted presenting complaints mentioned above. The estimated sample size is 3,906 patients. The primary outcome measurement for comparing the three types of care setting will be patient-reported outcome scores. The secondary outcome measurements will be: 1) patient-reported experience scores; 2) mean costs borne wholly by patients; 3) the proportion of return visits to any site 3 and 7 days after the initial visit; 4) the mean cost of care; 5) the incidences of mortality, hospital admissions and placement in intensive care within 30 days following the initial visit; 6) adherence to practice guidelines. Multilevel generalized linear models will be used to compare the care setting types and an overlap weights approach will be applied to adjust for confounding due to age, sex, gender, ethnicity, comorbidities, registration with a family physician, socioeconomic status and perceived severity of illness.

EXPERTISE This research project brings together a strong team with expertise in emergency and primary care, pneumonology, performance assessment, biostatistics, health economics, patient-oriented research, knowledge translation, administration and policymaking.

IMPORTANCE The endpoint of our program will be for policymakers, patients and care providers to be able to determine the most appropriate care setting for the management of ambulatory emergency conditions, based on the value of care associated with each alternative.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
4000
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Emergency departmentOn-site recruitment (information and consent) following a random sampling recruitment scheduleED care for acute ambulatory conditions by physicians unfamiliar with the patients.
Emergency departmentSecond phone call 8-14 days after the initial visitED care for acute ambulatory conditions by physicians unfamiliar with the patients.
Walk-in clinicsOn-site recruitment (information and consent) following a random sampling recruitment scheduleIn-person or virtual care in a walk-in clinic for acute ambulatory conditions by physicians unfamiliar with the patients. In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Walk-in clinicsFirst phone call 1-3 days after the initial visitIn-person or virtual care in a walk-in clinic for acute ambulatory conditions by physicians unfamiliar with the patients. In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Emergency departmentFirst phone call 1-3 days after the initial visitED care for acute ambulatory conditions by physicians unfamiliar with the patients.
Walk-in clinicsSecond phone call 8-14 days after the initial visitIn-person or virtual care in a walk-in clinic for acute ambulatory conditions by physicians unfamiliar with the patients. In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Primary care practiceFirst phone call 1-3 days after the initial visitIn-person or virtual care in a primary care clinic for acute ambulatory conditions (patients attached to a primary care practice, seen by their family physician or a colleague on a same-day appointment for urgent needs). In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Primary care practiceSecond phone call 8-14 days after the initial visitIn-person or virtual care in a primary care clinic for acute ambulatory conditions (patients attached to a primary care practice, seen by their family physician or a colleague on a same-day appointment for urgent needs). In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Primary care practiceOn-site recruitment (information and consent) following a random sampling recruitment scheduleIn-person or virtual care in a primary care clinic for acute ambulatory conditions (patients attached to a primary care practice, seen by their family physician or a colleague on a same-day appointment for urgent needs). In-person and virtual care will be assessed together as part of the care offer in outpatient clinics, but separately as a sub-analysis.
Primary Outcome Measures
NameTimeMethod
Median PROM-ED scoresAt 7 days after the initial visit measured at the 8-14 day follow-up call

The adapted PROM-ED provides a measurement of patient-reported outcome expressed as scores for symptom relief, reassurance and having a plan for care. Responses for each dimension are aggregated reported as a percentage, with a higher percentage signifying better health outcomes according to the patient

Secondary Outcome Measures
NameTimeMethod
Incidence of chest X-ray useFor the initial visit

Proportions of patients with URTI, bronchitis, asthma and back pain who had a chest X-ray performed. Obtained via electronic medical records.

Patient-reported experience measure (PREM) scoresAt the end of the initial visit measured at the 1-3 day follow-up call

The PREM evaluates the patient's view of care delivery and measures various dimensions of patient experience (e.g., attitude of providers). The main question for this primary outcome measure will be: "Would you recommend this place to your friends and family"? Most PREM questions are on a 5-level Likert scale.

Incidence of antibiotic or antiviral medication prescriptionFor the initial visit

Proportions of patients with URTI, otitis media, influenza or bronchitis who received a prescription for antibiotics or antiviral medication. Obtained via electronic medical records.

Mean cost of disease for patients (CoPaQ)At 7 days measured at the 8-14 day follow-up call

The adapted CoPaQ measures patients' and caregivers' out-of-pocket expenses (e.g., travel) and indirect costs (e.g., loss of income).

Incidence of return visitAt 7 days after the initial visit

Proportion of patients returning to any ED or outpatient clinic at 72 h and 7 days after the initial visit. Return visit occurrences will be identified via provincial physician billing databases.

Mean cost of care - Health care system perspectiveAt 72 hours and 7 days after the initial visit

Cost per care episode from the public payer's perspective calculated by summing the costs of all care processes delivered to a patient during the initial visit plus the costs of return visits and/or admissions at 72 hours and 7 days. Costs will be measured with a time-driven activity-based costing method with data extracted from electronic medical records review and provincial billing databases.

Incidences of admission/intensive care unit/mortalityAt 7 and 30 days after the initial visit

Proportions of patients who were admitted to hospital or to the intensive care unit or died within 30 days after the initial visit. Obtained via electronic medical records review and provincial databases (Institut de la statistique du Québec and ICES).

Wait timesFor the initial visit

Median/mean length of stay and time spent waiting to see a physician obtained via electronic medical records

Incidence of oral corticosteroid prescriptionFor the initial visit

Proportion of patients with exacerbated asthma or COPD who received a prescription for oral corticosteroids. Obtained via electronic medical records

Incidence of narcotic prescriptionFor the initial visit

Proportions of patients with cervical, thoracic and lumbar back pain who received a prescription for narcotics. Obtained via electronic medical records.

Incidence of spine X-ray, CT scan or MRI useFor the initial visit

Proportions of patients with back pain who had a spine X-ray, CT scan or a magnetic resonance imaging (MRI) performed or prescribed. Obtained via electronic medical records.

Incidence of diagnostic spirometry prescriptionFor the initial visit

Proportions of spirometry prescribed for long-term \>40-year-old smokers (current or past) undiagnosed with COPD who present for an acute lower respiratory tract infection. Obtained via electronic medical records.

Mean greenhouse gas (GHG) emissions from patient transportation to consultation siteFor the initial visit

Calculated following the Québec Ministry of Environment "Guide to quantifying greenhouse gas emissions". Fuel consumption (in liters) will be estimated from patient transport modality and travel distance (in km) between home and consultation site. GHS emissions in kg of CO2 equivalent will be calculated by multiplying fuel consumption (L) by the appropriate emission coefficient (kg CO2 eq./L) depending on the transport modality used (e.g. car, bus). Distance obtained at the 8-14 day follow-up call.

Compliance to guidelines on use of antibioticsFor the initial visit

Proportions of compliance to provincial recommendations of antibiotic prescriptions for pneumonia, tonsillitis, acute exacerbation of COPD and urinary tract infection. Obtained via electronic medical records.

Trial Locations

Locations (7)

Kingston Health Sciences Centre

🇨🇦

Kingston, Ontario, Canada

Queen's Family Health Team

🇨🇦

Kingston, Ontario, Canada

CISSS de Lanaudière

🇨🇦

Joliette, Quebec, Canada

CIUSSS-Nord de Montréal

🇨🇦

Montréal, Quebec, Canada

CIUSSS de la Capitale-Nationale

🇨🇦

Québec, Canada

Centre de recherche CHU de Québec - Université Laval

🇨🇦

Québec, Canada

Ottawa Hospital

🇨🇦

Ottawa, Ontario, Canada

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