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临床试验/NCT05595278
NCT05595278尚未招募不适用

Detrmination of the Relationship Between Red Cell Distribution Width ,NT-proBNP and cTnT in Acute Myocardial Infraction Patients

Sohag University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2022年11月13日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1
主要终点
(CBC)

研究概览

简要总结

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

详细描述

Patients and methods:

  • Type of study: Observational prospective study

  • Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.

  • Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.

  • Study Methods:

  • A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.

  • All patients included in the study will be subjected to:

  1. Full history:

  2. Personal history: e.g. age, sex and smoking.

  3. Family history of cardiac diseases

  4. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history

  5. Detailed clinical examination

  6. Electrocardiogram

  7. Laboratory investigation:

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • patients diagnosed as acute myocardial infarction and admitted to department of cardiology and cardiac care unit at Sohag cardiology and gastroenterology center according to inclusion and exclution criteria

排除标准

  • Patient with:
  • Decompensated heart failure
  • Pulmonary hypertention
  • Acute pulmonary embolism
  • Septic shock

结局指标

主要结局

(CBC)

时间窗: 6 months

measurement of CBC will be performed at the time of admission and by the time of discharge.

(cTnT)

时间窗: 6 months

measurement of cTnT levels will be performed at the time of admission and by the time of discharge

(NT-proBNP

时间窗: 6 months

measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hemat Kamel Maarouf

Resident doctor at clinical and chemical pathology department

Sohag University

研究点 (1)

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