Determination of the Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Not yet recruiting

• Conditions: Myocardial Infarction

• Registration Number: NCT05677503
• Lead Sponsor: Sohag University

Brief Summary

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Detailed Description

Patients and methods:

* Type of study: Observational prospective study

* Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.

* Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.

* Study Methods:

* A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.

1. Full history:

1. Personal history: e.g. age, sex and smoking.

2. Family history of cardiac diseases

3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history

2. Detailed clinical examination

3. Electrocardiogram

4. Laboratory investigation:

1. Routine investigation in the form of CBC including RDW

2. Specific investigation which include NT-proBNP and cTnT

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study First Submitted: 2022-12-23
• Status Verified: 2023-01
• Study First Submitted QC: 2023-01-09
• Study First Posted: 2023-01-10
• Last Update Submitted: 2023-01-11
• Last Update Posted: 2023-01-12
• Study Start: 2023-01-15
• Primary Completion: 2023-06-30
• Study Completion: 2023-07-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients diagnosed as acute myocardial infarction

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Exclusion Criteria

Patient with

• Decompensated heart failure
• Pulmonary hypertention
• Acute pulmonary embolism
• Septic shock

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Level of (NT-proBNP)	7 months	measurement of serum NT-proBNP level will be performed
complete blood count (CBC)	7 months	measurement of CBC levels will be performed
Level of (cTnT)	7 months	measurement of cTnT level will be performed