The Effect of Gum Acacia on Satiety, Glycemic Response and Gastrointestinal Tolerance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Blood glucose levels
研究概览
简要总结
This study will provide needed insight on the satiety and blood glucose and l effects of the soluble fiber gum acacia at 20g and 40g doses.
详细描述
This is a randomized, single-blind, crossover, intervention study testing the satiety and blood glucose effects of the soluble fiber gum acacia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
盲法说明
fiber will be mixed into orange juice
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 18 and 29 kg/m2
排除标准
- •distaste for bagels and cream cheese, orange juice or cheese pizza;
- •current smoker;
- •restrained eating habits;
- •recent weight change;
- •any history of disease or significant past medical history;
- •are vegetarian;
- •do not normally eat breakfast or lunch;
- •pregnant or lactating;
- •irregular menstrual cycles.
研究组 & 干预措施
0 fiber
0 grams fiber added to orange juice
干预措施: Placebo/Control (Other)
low fiber
20 grams of acacia gum added to orange juice
干预措施: Low Fiber (Other)
high fiber
40 grams of acacia gum added to orange juice
干预措施: High Fiber (Other)
结局指标
主要结局
Blood glucose levels
时间窗: 0, 30, 60, 120, 180, and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment
Blood will be taken via finger stick
Appetite Sensation
时间窗: 15, 30, 45, 60, 90, 120, 180 and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment
Subjective visual analog scale (VAS) will be utilized to assess hunger, fullness and desire to eat
次要结局
未报告次要终点