Glycemic and Insulinemic Impact of Selected Canadian Beans

Not Applicable

Completed

• Conditions: Impaired Glucose Tolerance
• Interventions: Other: Starchy Foods; Other: Bean Type

• Registration Number: NCT02907190
• Lead Sponsor: Guelph Food Research Centre

Brief Summary

The objective of this study is to compare the glycemic and insulinemic response elicited by ½ cup servings of 6 beans to those elicited by ½ cup servings of mashed potato, macaroni, rice and corn.

Detailed Description

In order for a food to be able to claim a reduced glycemic response, it must be shown that a typical serving of the food elicits a significantly lower blood glucose responses compared to a serving of an appropriate control food. While many studies have examined the GI of beans, few studies have compared the glycemic impact of a typical serving of beans to a typical serving of other starchy foods. Therefore, there are insufficient data to allow for a claim that beans have a low glycemic response. In addition, in order to make a claim of a reduced glycemic response, regulatory agencies also require that the insulinemic response to a food is not disproportionately increased.

Study Timeline

• Study Start: 2016-03
• Status Verified: 2016-09
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Study First Submitted: 2016-09-15
• Study First Submitted QC: 2016-09-19
• Last Update Submitted: 2016-09-19
• Study First Posted: 2016-09-20
• Last Update Posted: 2016-09-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Male or non-pregnant females, 18-75 years of age, inclusive
• Body mass index (BMI) < 40 kg/m²
• Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial and to refrain from smoking for 12hr prior to each visit.
• Normal fasting serum glucose (<7.0mmol/L capillary corresponding to whole blood glucose <6.3mmol/L).
• Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.

Exclusion Criteria

• Failure to meet any one of the inclusion criteria
• Known history of AIDS, hepatitis, diabetes or a heart condition
• Subjects using medications or with any condition which might, in the opinion of Dr. Wolever, the Medical Director of GI Labs, either: 1) make participation dangerous to the subject or to others, or 2) affect the results.
• Major trauma or surgical event within 3 months of screening.
• Unwillingness or inability to comply with the experimental procedures and to follow GI Labs safety guidelines.
• Known intolerance, sensitivity or allergy to any ingredients in the study products.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Starchy Foods	Starchy Foods	1/2 cup serving of rice or paste or potato or corn will be eaten by participants on different study visit
Bean Type	Bean Type	Beans (black; cranberry; great northern; navy; pinto; red) soaked overnight and boiled. 1/2 cup serving eaten by participants at study visit

Primary Outcome Measures

Name	Time	Method
Glycemic Response	120 minutes	post prandial blood glucose response

Secondary Outcome Measures

Name	Time	Method
Insulin Response	120 minutes	post prandial blood insulin response

Trial Locations

Locations (1)

Glycemic Index Laboratories, Inc; 🇨🇦 Toronto, Ontario, Canada