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Gelatin supplementation around exercise and type 1 collagen synthesis

Not Applicable
Completed
Conditions
Collagen Synthesis
Musculoskeletal - Normal musculoskeletal and cartilage development and function
Registration Number
ACTRN12616001092482
Lead Sponsor
Australian Institute of Sport
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
8
Inclusion Criteria

Active individuals exercising 2-3x per week.

Exclusion Criteria

History of recurrent connective tissue, tendon or ligament injury or current injury which prevents the exercise task being completed.
Known allergy to animal gelatin.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in engineered ligament collagen content and mechanics. Engineered ligaments will be grown in serum taken a each time point for each treatment[Baseline and 1 hour post ingestion of treatment. This is assessed in arm 1 only.];Change in serum amino-terminal propeptide of collagen I (PINP) content over time in response to treatment and exercise[Pre treatment ingestion (baseline), 4, 24, 48, and 72 hours. This outcome is assessed in arm 2 only]
Secondary Outcome Measures
NameTimeMethod
Change in serum amino acid availability after the ingestion of the treatment[Pre treatment (basleline), 30 minutes, 1, 1.5, 2 and 3 hours post ingestion of treatment. This outcome is in relation to arm 1.]
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