Gelatin supplementation around exercise and type 1 collagen synthesis
Not Applicable
Completed
- Conditions
- Collagen SynthesisMusculoskeletal - Normal musculoskeletal and cartilage development and function
- Registration Number
- ACTRN12616001092482
- Lead Sponsor
- Australian Institute of Sport
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 8
Inclusion Criteria
Active individuals exercising 2-3x per week.
Exclusion Criteria
History of recurrent connective tissue, tendon or ligament injury or current injury which prevents the exercise task being completed.
Known allergy to animal gelatin.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in engineered ligament collagen content and mechanics. Engineered ligaments will be grown in serum taken a each time point for each treatment[Baseline and 1 hour post ingestion of treatment. This is assessed in arm 1 only.];Change in serum amino-terminal propeptide of collagen I (PINP) content over time in response to treatment and exercise[Pre treatment ingestion (baseline), 4, 24, 48, and 72 hours. This outcome is assessed in arm 2 only]
- Secondary Outcome Measures
Name Time Method Change in serum amino acid availability after the ingestion of the treatment[Pre treatment (basleline), 30 minutes, 1, 1.5, 2 and 3 hours post ingestion of treatment. This outcome is in relation to arm 1.]