Should pre-procedure oral vitamin C supplementation be considered in people with diabetes undergoing dental procedures?

Not Applicable

• Conditions: Dental decay; Diabetes; Hypovitaminosis C; Delayed wound healing; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Diet and Nutrition - Other diet and nutrition disorders; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12623001182684
• Lead Sponsor: Te Whatu Ora - Waitaha Canterbury

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-11-15
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

People attending the hospital outpatient dental department for full and partial dental extractions (both groups)
- Able to understand study and give full and informed consent
- Agree to collection of age, ethnicity and health data
- Willing / able to give a fasting blood and urine sample

Group of 30 people without diabetes
- HbA1c below 53 mmol/mol (7%)
- not on any diabetes related medication - such as insulin, metformin, sulphonylurea's, DPPIV inhibitors, GLP1 receptor agonists or SGLT2 inhibitors

Group of 30 people with diabetes
- HbA1c of 53 mmol/mol (7%) or greater

Exclusion Criteria

For both groups of participants:
- Unable to fast prior to the sample collection
- Unable to understand the informed consent or study requirements
- Unwilling to participate

Study & Design

• Study Type: Observational
• Study Design: Not specified