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Salivary cortisol level and antidepressant treatment outcome in patients with depressio

Not Applicable
Recruiting
Conditions
Mental and behavioral disorders
Registration Number
KCT0000683
Lead Sponsor
Chonnam National University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

1)Aged 20 or older
2)HAMD-17>=14
3)Can understand the objective of the study and sign informed consent
4)If the subject is woman of childbearing age, the patient who does not plan to become pregnant and who uses appropriate contraceptive method
5)With ability to perform the procedure of study, administration of drug, visit to thi clinic as study protocol or with caretaker or clear officer who can help to perform the study procedure((eg, family, social workers, social work, volunteer, or nurse)

Exclusion Criteria

1)history of significantly unstable or uncontrollable medical condition, 2)unavailability to perform the psychiatric examination due to an acute physical illness
3)currently diagnosed or had history of other psychiatric disorder on DSM-IV Axis I : bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder NOS)

4)history of organic mental disorder, epilepsy or other convulsive disorder
5)history of prescribing anticonvulsant
6)patients needed hospitalization due to the psychiatric condition other than depression( abuse/dependence of alcohol/other substance)
7)history of ECT for current depressive episode
8)Pregnancy or breastfeeding

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hamilton depression rating scale
Secondary Outcome Measures
NameTimeMethod
Clinical Global Impression
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