Efficacy of oral verses parenteral vitamin B12 therapy in children with Vitamin B12 deficiency anaemia

Government medical college and hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年5月1日

研究概览

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•1) Children of age group - 6 months to 18 years
•2) Anemia as defined by WHO.
•6-59 months â?? less than 110 g/l at sea level
•5-11 yearsâ?? less than 115 g/l at sea level
•12-14 yearsâ?? less than 120 g/l at sea level
•More than 15 yearsâ?? less than 130 g/l at sea level25
•Corrected haemoglobin concentration according to sea level correction factor for altitude.
•3) Serum vitamin B12 levels below 350 pg/ml OR Holotranscobalamin levels below 35 pmol/l 22,26 will be included in

•1. Children who have already received Vitamin B12.
•2. Children who are already taking micronutrient supplementation.
•3. Children with iron deficiency anemia
•(Iron deficiency will be defined by serum ferritin <12 micrograms/L in less than 5 years and <15 microgram/L for more than 5 years, in the absence of other conditions affecting serum ferritin level, particularly inflammation)
•4. Children who have received blood transfusion within last 1month.12
•5. Any critical illness with hemodynamic compromise or on life support measures.

发起方

Government medical college and hospital