Somatosensory Processing in Depression

Phase 4

Withdrawn

• Conditions: Depression
• Interventions: Procedure: simultaneous EEG/fMRI; Device: fMRI

• Registration Number: NCT00386893
• Lead Sponsor: Ludwig-Maximilians - University of Munich

Brief Summary

Aim of this study is to investigate neuronal differences (EEG/evoked potentials; functional MRI) between patients with major depression and healthy controls concerning brain activity after acute pain as well as changes of pain related brain activity during treatment with escitalopram.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-10
• Study First Submitted: 2006-10-10
• Study First Submitted QC: 2006-10-10
• Study First Posted: 2006-10-12
• Primary Completion: 2011-12
• Study Completion: 2011-12
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-13
• Last Update Posted: 2015-04-14

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Psychiatric in or outpatients with acute depressive episode
• Indication for pharmacological treatment

Exclusion Criteria

• Acute suicidal tendency
• Neurological or severe somatic disorders
• Women during pregnancy or lactation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Treatment as usual	simultaneous EEG/fMRI	simultaneous EEG/fMRI
Treatment as usual	fMRI	simultaneous EEG/fMRI

Primary Outcome Measures

Name	Time	Method
changes in evoked potentials/functional MRI from baseline to week 4	two assessments, at baseline and week 4

Trial Locations

Locations (1)

Department of Psychiatry and Clin. Radiology, Ludwig-Maximilian-University; 🇩🇪 Munich, Bavaria, Germany