The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty

Phase 4

Completed

• Conditions: Postoperative Pain; Knee Arthroplasty
• Interventions: Procedure: Adductor-Canal-Blockade with Ropivacaine; Procedure: Adductor-Canal-blockade with saline

• Registration Number: NCT01191593
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-08-30
• Study First Submitted QC: 2010-08-30
• Study First Posted: 2010-08-31
• Study Start: 2010-09
• Primary Completion: 2013-04
• Study Completion: 2013-04
• Status Verified: 2013-08
• Last Update Submitted: 2013-08-21
• Last Update Posted: 2013-08-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Revision Knee Arthroplasty in general anaesthesia
• American society of anesthesiologists (ASA) 1-3
• BMI 18-40
• Written informed consent

Exclusion Criteria

• Can not cooperate to the exam
• Do not speak or understand Danish
• Drug allergy
• Alcohol or drug abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Adductor-Canal-Blockade with ropivacaine	Adductor-Canal-Blockade with Ropivacaine	-
Adductor-Canal-blockade with saline	Adductor-Canal-blockade with saline	-

Primary Outcome Measures

Name	Time	Method
Pain during 45 degrees active flexion of the knee	4 hours postoperative	0-100 mm at a visual analogue scale (VAS), at 4 hours postoperative.

Secondary Outcome Measures

Name	Time	Method
Pain during 45 degrees active flexion of the knee	24 hours postoperative	0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative.
Pain during rest	24 hours postoperative	0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative.
Total morphine consumption	0-24 hours postoperative	Total morphine consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative.
Postoperative nausea	24 hours postoperative	Nausea score(0-3)at 24 hours postoperative.
Postoperative vomiting	0-24 hours postoperative	Number of vomiting episodes at the intervals 0-8, 8-24 and 0-24 hours postoperative.
Zofran consumption	0-24 hours postoperative	Total zofran consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative.
Sedation	24 hours postoperative	Sedation score (0-3) at 24 hours postoperative.

Trial Locations

Locations (1)

Department of Anaesthesia and Surgery, HOC, Rigshospitalet, Denmark; 🇩🇰 Copenhagen, København Ø, Denmark