The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty

Rigshospitalet, Denmark1 site in 1 country40 target enrollmentJanuary 2011

ConditionsPostoperative Pain Knee Arthroplasty

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Postoperative Pain
Sponsor: Rigshospitalet, Denmark
Enrollment: 40
Locations: 1
Primary Endpoint: Pain during 45 degrees active flexion of the knee
Status: Completed
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The objective of this study is to assess the efficacy of Adductor-Canal-Blockade on pain and morphine consumption after total knee arthroplasty. Our hypothesis is that the Adductor -Canal-Blockade is superior to placebo in reducing pain and morphine consumption after total knee arthroplasty.

Registry

clinicaltrials.gov

Start Date

January 2011

End Date

September 2011

Last Updated

14 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Rigshospitalet, Denmark

Responsible Party

Principal Investigator

Pia Jaeger

Rigshospitalet, Denmark

Eligibility Criteria

Inclusion Criteria

•Total Knee Arthroplasty in general anaesthesia
•BMI 18-40
•Written informed consent

Exclusion Criteria

•Can not cooperate to the exam
•Do not speak or understand Danish
•Drug allergy
•Alcohol or drug abuse
•Daily consumption of strong opioids

Outcomes

Primary Outcomes

Pain during 45 degrees active flexion of the knee

Time Frame: 1 hour postoperative

0-100 mm at a visual analogue scale (VAS), at 1 hour postoperative

Secondary Outcomes

Pain during 45 degrees active flexion of the knee(0-6 hours postoperative)
Pain during rest(1-6 hours postoperative)
A change in pain score in the ropivacaine group, after activating the block(30-60 minutes postoperative)
Total morphine consumption(30 minutes - 6 hours postoperative)
Postoperative nausea(1-6 hours postoperative)
Postoperative vomiting(1-6 hours postoperative)
Zofran consumption(1-6 hours postoperative)
Sedation(1-6 hours postoperative)