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Clinical Trials/NCT01104883
NCT01104883
Completed
Phase 4

The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty

Rigshospitalet, Denmark2 sites in 1 country70 target enrollmentAugust 2010
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ConditionsTotal Knee Arthroplasty

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Total Knee Arthroplasty
Sponsor
Rigshospitalet, Denmark
Enrollment
70
Locations
2
Primary Endpoint
Total morphine consumption
Status
Completed
Last Updated
15 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing morphine consumption and pain, and at the same time improving mobilisation after total knee arthroplasty.

Registry
clinicaltrials.gov
Start Date
August 2010
End Date
March 2011
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Total Knee Arthroplasty in spinal anaesthesia
  • •BMI 18-40
  • •Written informed consent

Exclusion Criteria

  • •Can not cooperate to the exam
  • •Do not speak or understand Danish
  • •Drug allergy
  • •Alcohol or drug abuse
  • •Daily consumption of strong opioids
  • •Unable to complete the Timed Up and Go test preoperatively

Outcomes

Primary Outcomes

Total morphine consumption

Time Frame: 0-24 hours postoperative

Total morphine consumption at the interval 0-24 hours postoperative.

Secondary Outcomes

  • Total morphine consumption(0-26 hours postoperative)
  • Pain during rest(0-26 hours postoperative)
  • Pain during 45 degrees active flexion of the knee(0-26 hours postoperative)
  • A change in pain in the placebo group(24-26 hours postoperative)
  • Postoperative nausea(0-26 hours postoperative)
  • Zofran consumption(0-26 hours postoperative)
  • Sedation(0-26 hours postoperative)
  • Mobilisation(20-26 hours postoperative)
  • Postoperative vomiting(0-26 hours postoperative)

Study Sites (2)

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