"A Comparison of the Efficacy of the Adductor-Canal-Blockade Versus the Femoral Nerve Block on Muscle Strength, Pain and Mobilization After Total Knee Arthroplasty: a Randomized Study

Rigshospitalet, Denmark1 site in 1 country54 target enrollmentNovember 2011

ConditionsTotal Knee Arthroplasty

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Total Knee Arthroplasty
Sponsor: Rigshospitalet, Denmark
Enrollment: 54
Locations: 1
Primary Endpoint: The difference in quadriceps muscle strength between the Adductor-Canal-Blockade and the femoral nerve block
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the Femoral Nerve Block on muscle strength, pain and mobilization after total knee arthroplasty. We hypothesize that the Adductor-Canal-Blockade has the same effect on pain and morphine consumption as the Femoral Nerve Block, but without the same reduction in quadriceps muscle strength.

Registry

clinicaltrials.gov

Start Date

November 2011

End Date

November 2012

Last Updated

13 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Rigshospitalet, Denmark

Responsible Party

Principal Investigator

Pia Jaeger

Rigshospitalet, Denmark

Eligibility Criteria

Inclusion Criteria

•BMI \> 18 og \< 40
•total knee arthroplasty in spinal anesthesia

Exclusion Criteria

•Can not cooperate to the exam
•Do not speak or understand Danish
•Drug allergy
•Alcohol or drug abuse
•Daily consumption of strong opioids
•Rheumatoid arthritis
•Intake of glucocorticoids
•Effect of spinal anesthesia stopped prior to performing the regional block

Outcomes

Primary Outcomes

The difference in quadriceps muscle strength between the Adductor-Canal-Blockade and the femoral nerve block

Time Frame: 24 h postoperatively

Secondary Outcomes

The difference in adductor muscle strength between the Adductor-Canal-Blockade and the Femoral Nerve Block(24 h postoperatively)
Pain during flexion of the knee(2-24 hours)
Pain at rest(2-24 hours)
Total morphine consumption(0-24 hours)
Postoperative nausea(2-24 hours)
Postoperative vomiting(0-24 hours)
Sedation(2-24 hours)
Zofran consumption(0-24 hours)
The difference in mobilization between the groups(24 hours)