Aortic atheroma burden and cognitive dysfunction after cardiac surgery
- Conditions
- AtherosclerosisCognitive dysfunction1000796310003216
- Registration Number
- NL-OMON30070
- Lead Sponsor
- Isala Klinieken
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
A sub-sample of patients included in the diagnostic trial A-view: *Diagnostic value of an innovative non-invasive diagnostic to determine the grade of atherosclerosis before sternotomy in patients scheduled for cardiac surgery*. Patients over 65 years, undergoing sternotomy for elective cardiac surgery will be included in this study.
Exclusion Criteria
Patients who undergo a re-operation or off-pump surgery, suffer from neurodegenerative disease or a known psychiatric disorder and patients who are thought to be inable to perform neurocognitive testing will be excluded from participation in the subsample.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary: The relation between atherosclerosis of the ascending aorta and<br /><br>neurocognitive function at three months after surgery.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The relation between atherosclerosis of the ascending aorta and neurocognitive<br /><br>function at discharge, stroke, transient ischemic attack, myocardial infarction<br /><br>and renal failure.</p><br>