Enhanced Recovery After Surgery Promotes the Rehabilitation of Patients With Acute Gastrointestinal Perforation, a Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 362
- 试验地点
- 1
- 主要终点
- change of the c-reactive protein in plasma
研究概览
简要总结
The enhanced recovery after surgery(ERAS) has been gradually extended from its initial colorectal surgery to almost all surgical fields. However, there are few reports about the application value of ERAS in emergency surgery. The goal of this clinical trial is to evaluate the value of ERAS in the perioperative period of acute gastrointestinal perforation. All the patients will be treated by emergency operation. The changes of CRP, PA, PCT in Plasma 1 hour before operation and 1,3,7 days after operation, the operation time, the amount of bleeding during operation, the recovery time of intestinal function and the time of the first meal after operation,the incidence of postoperative complications, the degree of postoperative pain, the time of first out-of-bed activity, fatigue and mental status, quality of life, the length and the cost of hospital stay will be monitored and recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 14 Years 至 80 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age≥14years old and ≤80 years old
- •The initial diagnosis is acute gastrointestinal perforation
排除标准
- •Patients with unconsciousness,or patients with past psychiatric history
- •Patients with shock and/or severe organ failure
- •Patients who are pregnant
- •Patients with severe spinal deformity who are unable to receive epidural anesthesia
研究组 & 干预措施
the enhanced recovery after surgery (ERAS) group
Patients were rehabilitated using the ERAS concept.
干预措施: The enhanced recovery after surgery (Behavioral)
the conventional surgical treatment (CST) group
Traditional treatment methods.
干预措施: Traditional treatment methods. (Behavioral)
结局指标
主要结局
change of the c-reactive protein in plasma
时间窗: 1, 3, and 7 days after surgery
change of the prealbumin in plasma
时间窗: 1, 3, and 7 days after surgery
change of the procalcitonin in plasma
时间窗: 1, 3, and 7 days after surgery
次要结局
未报告次要终点
研究者
Chunjie Liu
Professor
Hebei Medical University
