Metabolic Consequences of Cross-sex Hormonal Treatment in Transgender Persons
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Retrospective analysis of existing data collected as a part of the regular follow-up
研究概览
简要总结
Retrospective study in a single academic regional transgender referral center. Analyse VAT, body composition and metabolic parameters in non-obese transgender subjects one year after starting gender-affirming hormone therapy and in controls
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •hormonal contraception
- •previous gender-affirming hormonal treatment
- •previous gender-affirming surgery
- •recognized syndrome or chromosomal defect, known metabolic or inflammatory disease, skeletal dysplasia, or chronic corticosteroid treatment.
结局指标
主要结局
Retrospective analysis of existing data collected as a part of the regular follow-up
时间窗: Retrospective analysis of data between 2004 and 2019
Retrospective analysis of existing data :Anthropometric parameters, including systolic blood pressure (SBP), diastolic blood pressure (DBP), body weight and height at fasting state, were measured in all subjects at the occasion of the routine follow-up visits. Body mass index (BMI) was calculated as body weight in kilograms divided by the height in meter squared (kg/m2). Body composition parameters, including lean mass (LM), total body fat (BF), android and gynoid fat, and bone mineral content, were determined using dual-energy X-Ray absorbtiometry (DXA) (GE-Healthcare Lunar iDXA system), biochemical and routine hormonal analysis
次要结局
未报告次要终点