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Influenza Burden Assessment in the United States, July1997 - up to April 2009

Completed
Conditions
Influenza
Interventions
Other: Data collection
Registration Number
NCT01599390
Lead Sponsor
GlaxoSmithKline
Brief Summary

The study will assess the burden of severe influenza outcomes by age, risk status, and influenza subtype, in order to create a profile of the burden of influenza-related morbidity and mortality in United States from July 1997 to April 2009.

Detailed Description

This epidemiological study is a modelling of time series retrospectively extracted from multiple databases. Data will be extracted from existing electronic healthcare databases.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1
Inclusion Criteria
  • Recorded in the US NIS hospitalization data or the US National Vital Statistics System (NVSS) mortality data with a pre-specified diagnostic code.
Exclusion Criteria
  • Missing data in the following fields: age, primary discharge diagnosis, admission month (NIS) /month of death (NVSS), and status at discharge (alive / dead).

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Influenza GroupData collection-
Primary Outcome Measures
NameTimeMethod
Occurrences of potentially influenza-attributable hospitalization or death by age, risk status, region and season.From July 1997 to April 2009 (i.e., up to almost 12 years)
Amount of circulating influenza A and B, and RSV strains determined for each season.From July 1997 to April 2009 (i.e., up to almost 12 years)
Secondary Outcome Measures
NameTimeMethod
Influenza vaccine content and effectiveness by season.From July 1997 to April 2009 (i.e., up to almost 12 years)
Influenza vaccine coverage by season.From July 1997 to April 2009 (i.e., up to almost 12 years)
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