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Short Term Magnesium Preventation In Menstrually Related Migraine (MRM)

Phase 3
Conditions
Menstrually Related Migraine (MRM).
Registration Number
IRCT20190415043284N1
Lead Sponsor
Ahvaz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
60
Inclusion Criteria

patients affected by menstrually related migraine according to 3rd edition of The International Classification of Headache Disorders
regular mense

Exclusion Criteria

chronic diarrhea
renal failure
nephrolithiasis
myasthenia gravis patients
anti hypertensive drug usage particularly calcium channel blocker users
diabetic patients who has insulin resistance state
pregnancy or planned pregnancy; ; menstrual migraine [14]
breast feeding women
non migraine headache
psychiatric illness according to DSM5 criteria
chronic systemic illness
dependence or abuse of drugs
intake of antidepressants, neuroleptics, minor or major tranquillizers, drugs used for the treatment of affective disorders (e.g. lithium, carbamazepine), antiepileptics
bradrychardia
anti coagulant and antiplatelet usage
pure menstrually migraine

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Headache attacks of menstrually related migraine. Timepoint: 4 questionnaires are filled: the first one at the sampling time and 3 others during 3 continuous menstrual cycles which the participant take pills. Method of measurement: questionnaire.
Secondary Outcome Measures
NameTimeMethod
Headache frequency, intensity, prolongation, amount of analgesic drugs and resulting palliation. Timepoint: 4 questionnaires are filled: the first one at the sampling time and 3 others during 3 continuous menstrual cycles which the participant take pills. Method of measurement: Each questionnaire contains a calendar with blanks to record: the exact date of menstruation starting date, headache days, headache intensity ( 1 to 10 scale), each headache attack prolongation (hours), number of analgesic pills to pain relief and resulting palliation (describes with excellent, good, intermediate and poor response).
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