Total brain perfusion 320 row CT application in acute, subacute and chronic stroke

• Conditions: Ischaemic Stroke; I63; Cerebral infarction

• Registration Number: DRKS00000616
• Lead Sponsor: CSB-Centrum für Schlaganfallforschung

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01-03
• Study Completion: 2016-06-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting stopped after recruiting started
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

>Acute (symptomonset <24h) stroke in the territory of the medial cerebral artery (MCA) territory
--> subacute stroke (symptomonset >24h-14d)
--> chronic stroke (> 14d)
--> < 2/3 infarction of the medial cerebral artery (MCA) territory
--> Age 50-85
--> NIHSS =2

Exclusion Criteria

--> contraindications for MRI (e.g. magnetic implants, pacemaker)
--> claustrophobia
--> critical clinical condition
--> missing capacitiy to contract (loss of conciousness, severe aphasia)
--> infarct in the posterior circulation
--> hypothyreosis
--> allergic reaction on contrast agent
--> renal failure (creatinin clearance >0,9 mg/dl)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
This study is a pilot study. Thus, the exact definition of endpoints is not possible. After the imaging procedures the trail is finished. The definition of hypoperfusion on 320 row pCT will be compared to dw/pw MRI in a voxel based analysis

Secondary Outcome Measures

Name	Time	Method
ot applicable for this trial