MedPath

Effects off Rheum ribes L. syrup on bloody diarrhea

Phase 2
Conditions
Bloody diarrhoea.
Shigellosis
Registration Number
IRCT2014070518356N1
Lead Sponsor
Vice Chancellor for research, Shahid Sadoughei University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
94
Inclusion Criteria

Inclusion criteria : (1) age between 12 to72 months; (2) history of passing loose stool (>3 times per day) mixed with blood and or mucus for =72 hours or>5 WBC in S/E, and (3) with or without the presence of fever, abdominal pain, anorexia, dehydration, and vomiting; (4) written, voluntary informed consents from the parent or legal guardians of the children were obtained at the time of admission. Exclusion criteria:(1) refusal of consent by parents; (2) treatment with an antimicrobial and or antidiarrheal agents within last 3 days; (3) fecal presence of erythrophagocytic trophozoite of Entameba histolytica or cyst/trophozoites of Giardia lamblia; (4) presence of concurrent illnesses (pneumonia, sepsis, meningitis, and toxic colitis).

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood in stool. Timepoint: Before intervention and eyery 8 hours after intervention. Method of measurement: Direct inspection and asking patient`s parents.;Fever. Timepoint: At the beginning and then every 8 hours. Method of measurement: Thermometer.;Daily numbers of stools. Timepoint: Every 8 hours. Method of measurement: Asking from nurse of pationt.;RBC in stool. Timepoint: In days 0, 3, 5. Method of measurement: Stool Exams.
Secondary Outcome Measures
NameTimeMethod
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