on-surgical periodontal therapy in rheumatoid arthritis patients

Completed

• Conditions: Chronic periodontitis; Oral Health

• Registration Number: ISRCTN60187959
• Lead Sponsor: niversity of Medicine and Pharmacy Cluj-Napoca

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11-24
• Last Update Posted: 19 December 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Moderate or severe chronic periodontitis; >30 years of age
2. =10 natural teeth present in the oral cavity
3. Full-mouth plaque scores (FMPS) =30% after oral hygiene instructions
4. No other systemic diseases or medications except for RA, which are known to influence periodontal conditions/treatment outcome (e.g. Down Syndrome, HIV, Diabetes Mellitus type 1 and 2)
5. DAS28=3.2
6. No infectious or heart diseases that need prophylactic administration of antibiotics before dental treatment
7. No liver disease; no head and neck radiation therapy

Exclusion Criteria

1. Non-surgical periodontal therapy within the previous 12 months
2. Systemic or local use of antibiotics within the previous 3 months
3. Medication with a possible influence on the periodontium (e.g., ciclosporines, phenytoines, calcium channel blockers)
4. Pregnancy or lactation

In the RA group, RA was diagnosed according to the criteria set by the American College of Rheumatology;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The decrease of CRP in the patients with rheumatoid arthritis at 3 months (The CRP level, measured as counts, was determined from blood samples in the laboratory of the Clinic of Rheumatology of the University Iuliu Hatieganu Cluj-Napoca).<br>