Tranexamic acid to reduce blood loss at unplanned caesarean delivery
Not Applicable
- Conditions
- nplanned caesarean deliveryPregnancy and Childbirth
- Registration Number
- ISRCTN17814519
- Lead Sponsor
- niversity Malaya Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- Female
- Target Recruitment
- 322
Inclusion Criteria
1. Age =18 years old
2. At term (= 37 weeks)
3. Able to fully understand Malay or English
4. Live fetus
5. Emergency/unplanned CS in labour (contractions = 2 in 10 min, cervix = 3 cm)
Exclusion Criteria
1. Clinical indication for tranexamic acid
2. Contraindication to tranexamic acid
3. Known hypersensitivity to tranexamic acid
4. Known placenta previa/placenta accreta spectrum
5. Contraindications to tranexamic acid
6. Suspected current thromboembolic events
7. Known thrombophilia, coagulopathy or severe renal disease
8. History of venous thromboembolism
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Calculated total blood loss measured using data collected from hospital laboratory records on preoperative (most recently within 8 days before surgery) and postoperative (closest to day 2 after delivery) haematocrit values
- Secondary Outcome Measures
Name Time Method