Effects of Crossover Point Exercise and High-intensity Interval Training on Vascular Health in Young Overweight Females
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- brachial-ankle pulse wave velocity (baPWV)
Study Overview
Brief Summary
The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.
Detailed Description
In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 30 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Female, 18-30 years old
- •Body mass index (BMI) < 28 kg/m2 and ≥ 24 kg/m2
- •No exercise habit, and no recent new exercise plan
- •No contraindications to exercise
Exclusion Criteria
- •Participates had an orthopedic or other condition that limited participation in daily exercise
- •Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer
- •Participates had smoking or alcohol behavior
Arms & Interventions
HIIT group
Intervention: high-intensity interval training (HIIT) (Behavioral)
COP group
Intervention: crossover point(COP) exercise training (Behavioral)
Outcomes
Primary Outcomes
brachial-ankle pulse wave velocity (baPWV)
Time Frame: 10 weeks
The change of baPWV before and after intervention
blood pressure
Time Frame: 10 weeks
The change of blood pressure before and after intervention
Secondary Outcomes
- Interleukin 6 (IL-6)(10 weeks)
- Homocysteine (HCY)(10 weeks)