Effects of COP Exercise and HIIT on Vascular Health in Young Overweight Females

Not Applicable

Completed

• Conditions: Vascular Diseases

• Registration Number: NCT05817487
• Lead Sponsor: Beijing Sport University

Brief Summary

The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.

Detailed Description

In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.

Study Timeline

• Study Start: 2019-02-18
• Primary Completion: 2019-07-05
• Study Completion: 2019-10-25
• Status Verified: 2023-04
• Study First Submitted: 2023-04-05
• Study First Submitted QC: 2023-04-05
• Last Update Submitted: 2023-04-05
• Study First Posted: 2023-04-18
• Last Update Posted: 2023-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

1. Female, 18-30 years old
2. Body mass index (BMI) < 28 kg/m2 and ≥ 24 kg/m2
3. No exercise habit, and no recent new exercise plan
4. No contraindications to exercise

Exclusion Criteria

1. Participates had an orthopedic or other condition that limited participation in daily exercise
2. Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer
3. Participates had smoking or alcohol behavior

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
brachial-ankle pulse wave velocity (baPWV)	10 weeks	The change of baPWV before and after intervention
blood pressure	10 weeks	The change of blood pressure before and after intervention

Secondary Outcome Measures

Name	Time	Method
Interleukin 6 (IL-6)	10 weeks	The change of IL-6 level before and after intervention
Homocysteine (HCY)	10 weeks	The change of HCY level before and after intervention

Trial Locations

Locations (1)

Beijing Sport University; 🇨🇳 Beijing, China