AgeTLIF - Assessing Risk Factors for Radiological Complications After Transforaminal Lumbar Interbody Fusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- Number of Implant failure
研究概览
简要总结
This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the need for revision surgery increases with age.
详细描述
Spinal fusion is one of the most commonly performed surgical procedures for the treatment of degenerative spinal disease. Interbody fusion with cages reconstructs the anterior column through disc removal, allowing to maintain proper disc height despite weight bearing, while providing firm fixation of the spinal segments. Transforaminal lumbar interbody fusion (TLIF) has fewer complications and less intraoperative bleeding than posterior lumbar interbody fusion (PLIF). Elderly patients are at high risk for perioperative and postoperative complications after lumbar fusion. This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the need for revision surgery increases with age.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Indications for TLIF surgery (e.g., degenerative disc disease, spondylolisthesis)
- •Existing preoperative upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis, sacrum and femoral head
- •Existing preoperative MRI of the lumbar region with clear visibility of different fatty infiltration grade and stenosis degree
- •Complete follow-up at 3 months and 1 year postoperatively, including clinical and radiographic data
排除标准
- •Neuromuscular diseases such as Parkinson's disease or multiple sclerosis according to our records
- •Preoperative infection and/or malignancy tumor with involvement of the bony or soft tissue structures of the lumbar spine
- •Presence of a documented consent dissent
结局指标
主要结局
Number of Implant failure
时间窗: one time assessment at baseline
Number of Implant failure (screw loosening, cage subsidence, adjacent level alteration/ degeneration, spondylolisthesis degree, kyphosis of the adjacent intervertebral disc space, reduced height of intervertebral disc space) in relationship to age
Number of patients needing revision surgery
时间窗: one time assessment at baseline
Number of patients needing revision surgery, in relationship to age
次要结局
未报告次要终点