Protective Effect of Propofol Against Hemolysis in Patients Submitted to Gastroplasty
Not Applicable
- Conditions
- Hemolysis
- Registration Number
- NCT00792779
- Lead Sponsor
- Centro Medico Campinas
- Brief Summary
The purpose of this study is to determine if propofol could protect erythrocytes by directly scavenging free radicals from the blood current and increasing resistance of their cell membranes in patients submitted to gastroplasty.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- patients between BMI 40-50 kg/m2
Exclusion Criteria
- patients with BMI under 40 kg/m2 and over 50 kg/m2
- alcohol users
- illicit-drug users
- patients in regular use of anti-depressants, proton bomb inhibitors or calcium canal blockers
- patients transfused either recently, during the intra-operative period or within 10 hours post-operative
- patients previously known to be hypersensitive to any drug that is used during the study
- patients with any psychiatric disorder or dementia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Count erythrocytes After 10 hours post-surgery
- Secondary Outcome Measures
Name Time Method Bilirubins(direct and indirect) After 10 hours post-surgery
Trial Locations
- Locations (1)
Fundação Centro Médico de Campinas
🇧🇷Campinas, São Paulo, Brazil