Does the anaesthetic drug propofol affect the blood levels of the endogenous cannabis-like substance anandamide?

Not Applicable

Recruiting

• Conditions: peri-operative Anandamide Plasma Levels; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12611000361909
• Lead Sponsor: Thomas Ledowski

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

patients scheduled for minor non-emergency surgery

Exclusion Criteria

Age < 18 yrs and > 65 yrs, ASA physical status > 2 (= significant comorbidity), history of chronic pain, a contraindication for any of the used drugs, and the incapacity to consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anandamide Plasma levels[T0: Baseline (pre-operatively)<br>T1: 15 minutes after induction of anaesthesia<br>T2: 5 minutes after cessation of sevoflurane or propofol<br>T3: 25 minutes after T2<br>T4: 55 minutes after T2]

Secondary Outcome Measures

Name	Time	Method
nil[nil]