Population pharmacokinetics of propofol infusio

Phase 3

• Conditions: General anesthesia.; Other and unspecified general anaesthetics; Y 48.2

• Registration Number: IRCT2013063012365N2
• Lead Sponsor: Ahvaz Jundishapour University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

ASAclass-1; Age between15-55 years.
Exclusion criteria: ASAclass-2; Addiction; Liver, kidney, cardiac disease; Sensivity for egg; Hemodynamic instability.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma concentration of propofol. Timepoint: If possible blood samples are collected at 0, 2, 5, 10, 15, 30, 45, 60 minutes during infusion and then 0, 2, 5, 10, 15, 30, 45, 60, 120, 180 minutes after the end of infusion. Method of measurement: Blood sampling with the volume of 2ml and analyzing the concentration with HPLC.;Weight. Timepoint: Before transfering to operation room. Method of measurement: Scale.;Height. Timepoint: Before transfering to operation room. Method of measurement: Meter.;Age. Timepoint: Before transfering to operation room. Method of measurement: Match with birth certificate.;Sex. Timepoint: Before transfering to operation room. Method of measurement: Match with birth certificate.