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The phase II study of AboundTM against oral mucositis induced by chemoradiotherapy for head and neck cancer patients

Phase 2
Conditions
head and neck cancer
Registration Number
JPRN-UMIN000016453
Lead Sponsor
Shizuoka Cancer Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
35
Inclusion Criteria

Not provided

Exclusion Criteria

i. Opioid use before initiation of chemoradiotherapy ii. Use of AboundTM before initiation of chemoradiotherapy iii. Patients who will receive palliative chemoradiotherapy iv. Serious comorbidities include the following: a. Renal failure b. Disseminated intravascular coagulation c. Acute thrombocytopenia d. Chronic obstructive pulmonary disease e. Interstitial pneumonia f. Severe heart disease, such as ischemic heart disease and arrhythmia v. Women who are pregnant, contemplating pregnancy or amid breast-feeding. vi. Mental disorders which is considered inappropriate for inclusion in the study. vii. Continuous systemic treatment with corticosteroids viii. Signs of acute bacterial or fungus infection ix. Protein intake restriction x. Patients who are taking supplement or drugs containing Arginine or Glutamine, and who will continue to take them throughout the chemotherapy xi. Hypersensitivity to the element of AboundTM xii. Unable to take AboundTM per oral or per PEG xiii. Any other cases who are regarded as inadequate for study enrollment by the investigator

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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