Biomarkers of Sepsis

Completed

• Conditions: blood poisoning; sepsis; 10002252

• Registration Number: NL-OMON36012
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 500

Inclusion Criteria

- Age > 18 years
- Presence of an arterial line
- Patients who score positive for sepsis according to the Bone criteria (at least 2 SIRS criteria plus clinical suspicion of infection).

Exclusion Criteria

- No informed consent.
- Patients receiving > 48 hours of antibiotic treatment for a suspected infection prior to ICU admission.
- Previous participation in this study.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Endpoints include pathogen etiology, systemic inflammatory parameters and MODS.<br /><br>The endpoints will enable us to develop a predictive model for risk<br /><br>stratification for sepsis and provides insight in the pathophysiologic<br /><br>processes of sepsis and might lead to novel therapeutic interventions. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>