Eggs as Part of a Healthy Breakfast: Lack of Association With Heart Disease Risk
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Spectrophotometry, NMR and ELISA will assess plasma lipids.
研究概览
简要总结
Contrary to popular belief, previous studies have demonstrated beneficial effects of whole egg consumption in modifying biomarkers indicative of a greater risk of coronary heart disease (CHD), chronic inflammation, and insulin resistance. The following study is designed to conduct a comprehensive evaluation of consuming an egg-based breakfast compared to an oatmeal-based breakfast on lipid biomarkers, oxidative stress, inflammation, insulin sensitivity, and satiety in young, healthy men and women. The investigators hypothesize that the consumption of 2 eggs per day will not negatively impact plasma lipids in a young, healthy population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI 18.5-30, willing to consume eggs and oatmeal daily, proficient in English, and with a healthy lipid profile.
排除标准
- •Currently have liver disease, renal disease, diabetes, cancer, history of stroke or heart disease
- •Currently taking glucose lowering drugs or supplements
- •Plasma triglycerides >500 mg/dL, glucose >126, total cholesterol >240
- •Pregnant, lactating, or have endocrine or metabolic disorders
- •Blood pressure > 140/90 (average of 3 readings)
- •Allergies to eggs
- •Celiac disease or gluten sensitivity
研究组 & 干预措施
Eggs - 2 per day for breakfast
Participants will consume 2 eggs per day for breakfast for 4 weeks of the study.
干预措施: Eggs - 2 per day for breakfast (Other)
Eggs - 2 per day for breakfast
Participants will consume 2 eggs per day for breakfast for 4 weeks of the study.
干预措施: 1 packet of oatmeal per day (Other)
Oatmeal - 1 packet per day for breakfast
Participants will consume 1 packet of oatmeal per day for breakfast for 4 weeks of the study.
干预措施: Eggs - 2 per day for breakfast (Other)
Oatmeal - 1 packet per day for breakfast
Participants will consume 1 packet of oatmeal per day for breakfast for 4 weeks of the study.
干预措施: 1 packet of oatmeal per day (Other)
结局指标
主要结局
Spectrophotometry, NMR and ELISA will assess plasma lipids.
时间窗: 1 year
次要结局
- Visual analog scales (VAS) and ELISA assays will assess satiety.(1 year)
研究者
Maria Luz Fernandez
Professor
University of Connecticut