Effects of a Specific Spice on Energy Metabolism

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Dietary Supplement: Mustard (dijon); Dietary Supplement: Placebo

• Registration Number: NCT00841893
• Lead Sponsor: University of Copenhagen

Brief Summary

The objective of this study is to examine whether a specific spice is capable of affecting energy metabolism.

Since chili and other spices have been shown to increase energy expenditure and in some cases also affect energy intake/appetite compared to placebo, the investigators expect that the specific spice may actually increase energy expenditure and potentially also decrease appetite - although not to a large degree.

Detailed Description

Several pungent food ingredients, such as chili, and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food, since a few studies have suggested an effect of bioactive ingredients on appetite/energy intake. We expect to see some small effects on these parameters.

Study Timeline

• Study Start: 2008-08
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Status Verified: 2009-02
• Study First Submitted: 2009-02-10
• Study First Submitted QC: 2009-02-10
• Last Update Submitted: 2009-02-10
• Study First Posted: 2009-02-11
• Last Update Posted: 2009-02-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 16

Inclusion Criteria

• male
• healthy and not using medication (regularly)
• normal weight
• non-smoker
• tolerate and like spicy food
• stable body weight last two months

Exclusion Criteria

• increased blood pressure
• mental, metabolic and chronic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	Mustard (dijon)	Mustard
2	Placebo	Placebo

Primary Outcome Measures

Name	Time	Method
Energy expenditure (resting)/Meal-induced thermogenesis	November 2008

Secondary Outcome Measures

Name	Time	Method
VAS-scores for different appetite parameters (incl. satiety, hunger, fullness, prospective food intake, well-being, thirst etc.)	November 2008
Blood pressure	November 2008
Heart rate	November 2008
Substrate oxidation (fat and carbohydrate)	November 2008

Trial Locations

Locations (1)

Department of Human Nutrition, Faculty of Life Sciences, university of Copenhagen; 🇩🇰 Frederiksberg C, Copenhagen, Denmark