Hereditary sensory neuropathy type 1 (HSN1) treatment trial.

Not Applicable

Recruiting

• Conditions: Hereditary sensory neuropathy type 1A with SPTLC1 mutations; Hereditary sensory neuropathy type 1B with SPTLC2 mutations; Neurological - Neurodegenerative diseases; Human Genetics and Inherited Disorders - Other human genetics and inherited disorders

• Registration Number: ACTRN12619000561189
• Lead Sponsor: Concord Repatriation General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-10
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Participants tested positive to SPTLC1 mutations.
-Participants showing signs and symptoms of HSN1.
-Participants able to visit the clinic in Sydney, Australia (geographically close proximity).
-Ambulant subjects.
-Participants only taking part in 1 clinical trial at a time.
-Participants that are able to provide acceptable/accurate reproducible sensory level measurements.

Exclusion Criteria

-Participants whom have the presence of other forms of neuropathy e.g.-diabetes.
-Participants already taking L-serine.
-Participants highly dependent on medical care.
-Participants with severe nerve degeneration.
-Existing alcohol or drug abusers.
-Pregnant women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified