Evaluation of effect of probiotic in the treatment of cancer sores

Phase 2

• Conditions: Recorrent oral aphthae; K12.0

• Registration Number: RBR-4w2jc2
• Lead Sponsor: niversidade Federal de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-10-30
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with a history of recurrent aphthous stomatitis (RAS) with age between 18 to 60 years, both genders; suffering from RAS for at least one year, with ulcers at least once a month; who had signed informed consent.

Exclusion Criteria

Patients with a history of EAR under age of 18 or over 60 years; chronic smokers or alcoholics ; pregnancy or it suspicion ; patients with current or previous malignancies ; undergoing chemotherapy or radiotherapy ; suspected or history of congenital or acquired immunodeficiency ; under suspected or history of Crohn's disease or other inflammatory bowel diseases ; suspected or history of periodic fever syndrome associated with aphthous stomatitis , pharyngitis and cervical adenitis ( PFAPA ) , Reiter's syndrome , or suspected Behcet's disease; suspected or history of any vitamin or nutritional deficiency , cyclic neutropenia , anemia and autoimunes diseases , chronic use of drugs such as nonsteroidal anti esterioidais , immunosuppressants ( azathioprine , cyclosporine , corticosteroids , interferons ) , anxiolytics , antidepressants or nicorandil ; diseases such as renal failure , liver failure , hyperthyroidism or hypothyroidism , in the use of any type of food with probiotics and fiber supplements and antidiarrheal medications or laxatives regularly.

Study & Design

• Study Type: Intervention
• Study Design: Not specified