Study of patients with severe high blood pressure referred to hospital for same-day specialist review

Not Applicable

• Conditions: Hypertension; Circulatory System

• Registration Number: ISRCTN40430183
• Lead Sponsor: niversity of Nottingham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-10-05
• Last Update Posted: 19 October 2020
• Study Completion: 2038-10-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

1. Adults aged 18 and over
2. Severe hypertension (systolic >180 mmHg and/or diastolic >110 mmHg)
3. Referred for same-day specialist review (for cases only)

Exclusion Criteria

1. Pre-existing renal replacement therapy
2. Acute stroke

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> A combined primary outcome of:<br> 1. Stroke measured by review of electronic health records at 1, 2, 5 and 10 years<br> 2. MI measured by review of electronic health records at 1, 2, 5 and 10 years<br> 3. Change in eGFR measured by review of electronic health records at 1, 2, 5 and 10 years<br> 4. Need for renal dialysis measured by review of electronic health records at 1, 2, 5 and 10 years<br> 5. Mortality measured by review of electronic health records at 1, 2, 5 and 10 years<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Rehospitalisation within 2 years, measured by review of electronic health records at 1, 2, 5 and 10 years<br> 2. Diagnosis of accelerated hypertension within 10 years, measured by review of electronic health records at 1, 2, 5 and 10 years<br>